Publications

Smith JS, Valentino TR, Ablicki AH, Banerjee R, Colligan AR, Eckert DM, Desjardins GA, Diehl KL* (2024). A genetically-encoded fluorescent biosensor for visualization of acetyl-CoA in live cells. Biorxiv.https://www.biorxiv.org/content/10.1101/2023.12.31.573774v2.full

Heard S, Diehl KL, Winter JM (2023). Biosynthesis of the fungal nonribosomal peptide penilumamide A and biochemical characterization of a pterin-specific adenylation domain. RSC Chemical Biology, DOI: 10.1039/D3CB00088E.

Garrison A. Nickel and Katharine L. Diehl* (2022). Chemical Biology Approaches to Identify and Profile Interactors of Chromatin Modifications. ACS Chem. Biol. Published 3 March 2022.

Diehl KL, Muir TW (2020). Chromatin as a key consumer in the metabolite economy. Nat Chem Biol, 16(6), 620-629.

Diehl, KL, Ge, EJ, Weinberg, DN, Jani, KS, Allis, CD, Muir, TW (2019). PRC2 engages a bivalent H3K27M-H3K27me3 dinucleosome inhibitor. Proc Natl Acad Sci U S A, 116(44), 22152-22157.

Ge EJ, Jani KS, Diehl KL, Müller MM, Muir TW (2019). Nucleation and Propagation of Heterochromatin by the Histone Methyltransferase PRC2: Geometric Constraints and Impact of the Regulatory Subunit JARID2. J Am Chem Soc, 141(38), 15029-15039.

Jain SU, Do TJ, Lund PJ, Rashoff AQ, Diehl KL, Cieslik M, Bajic A, Juretic N, Deshmukh S, Venneti S, Muir TW, Garcia BA, Jabado N, Lewis PW (2019). PFA ependymoma-associated protein EZHIP inhibits PRC2 activity through a H3 K27M-like mechanism. Nat Commun, 10(1), 2146.

Jani KS, Jain SU, Ge EJ, Diehl KL, Lundgren SM, Müller MM, Lewis PW, Muir TW (2019). Histone H3 tail binds a unique sensing pocket in EZH2 to activate the PRC2 methyltransferase. Proc Natl Acad Sci U S A, 116(17), 8295-8300.

Liszczak G,* Diehl KL,* Dann GP, Muir TW (2018). Acetylation blocks DNA damage–induced chromatin ADP-ribosylation. Nat Chem Biol, 14(9), 837–840.

*authors contributed equally

Dann GP, Liszczak GP, Bagert JD, Müller MM, Nguyen UTT, Wojcik F, Brown ZZ, Bos J, Panchenko T, Pihl R, Pollock SB, Diehl KL, Allis CD, Muir TW (2017). ISWI chromatin remodellers sense nucleosome modifications to determine substrate preference. Nature, 548(7669), 607-611.

Diehl KL, Bachman JL, Anslyn EV (2017). Tuning thiol addition to squaraines by ortho-substitution and the use of serum albumin. Dyes and Pigments, 141, 316-324.

Li X, Zamora-Olivares D, Diehl KL, Tian W, Anslyn EV (2016). Differential sensing of oils by conjugates of serum albumins and 9,10-distyrylanthracene probes: a cautionary tale. Supramolecular Chemistry, 29(4), 308-314.

Diehl KL, Kolesnichenko IV, Robotham SA, Bachman JL, Zhong Y, Brodbelt JS, Anslyn EV (2016). Click and chemically triggered declick reactions through reversible amine and thiol coupling via a conjugate acceptor. Nat Chem, 8, 968-973.

Diehl KL, Ivy MA, Rabidoux S, Petry SM, Müller G, Anslyn EV (2015). Differential sensing for the regio- and stereoselective identification and quantitation of glycerides. Proc Natl Acad Sci U S A, 112(30), E3977-86.

Diehl KL, Bachman JL, Chapin BM, Edupuganti R, Escamilla PR, Gade AM, Hernandez ET, Jo HH, Johnson AM, Kolesnichenko IV, Lim J, Lin C-Y, Meadows MK, Seifert HM, Zamora-Olivares D, Anslyn EV (2015). Design and Synthesis of Synthetic Receptors for Biomolecule Recognition. In Bradley Smith (Ed.), Synthetic Receptors for Biomolecules: Design Principles and Applications (pp. 39-85). The Royal Society of Chemistry.

Barman S, Diehl KL, Anslyn EV (2014). The effect of alkylation, protonation, and hydroxyl group substitution on reversible alcohol and water addition to 2- and 4-formyl pyridine derivatives. RSC Advances, 4(55), 28893-28900.

Diehl KL, Anslyn EV (2013). Array sensing using optical methods for detection of chemical and biological hazards. Chem Soc Rev, 42(22), 8596-611.